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24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal AgroParisTech Université Paris-Saclay SAPS - Sciences Animales Paris-Saclay


GABI : Génétique Animale et Biologie IntégrativeUnité Mixte de Recherche INRA - AgroParisTech

Research highlights for 2020: an illustration of our main research results

Research Highlights
The research highlights presented here illustrate the significant results achieved by the GABI unit each year and published in international scientific peer review journals.
Light microscope observation of G. mellonella larvae infected with B. cereus associated with Cry1C toxin 16 hours after force-feeding. Cross–sections (16 µm) (cresyl violet staining and ethanol and xylene dehydration) with focus on the intestine (midgut). The bacteria appear colored as dark or brighter violet. Different magnifications are shown: (a) 4×; (b)10×; (c) 20×, and (d) 40×. (lum: intestinal lumen; bac: bacteria; gEpi: Gut Epithelium; pm: Peritrophic matrix

Laser microdissection allows fine in situ analysis of the interaction between extracellular bacteria and the host

Laser capture microdissection to study Bacillus cereus iron homeostasis gene expression during Galleria mellonella in vivo gut colonization.
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@INRAE D. Boichard

Publication of dairy catlle indexes estimated with the "Single Step" method

Single Step is a genomic evaluation method that simultaneously uses all animals, whether genotyped or not, in only one step. It is a major evolution...
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@INRAE - Sandrine Floriot (Impact de la troncation de la protéine C-Nap1 Bovin vs Murin)

C-Nap1, from the cow to the mouse, a centriolar protein gradually reveals its secrets

A study of the Caprine-like Generalized Hypoplasia Syndrome (SHGC) in the Montbeliard breed identified a mutation leading to the truncation of the...
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Publication Clin Epigenet, Costes & al.

Predicting male fertility from sperm methylome: application to 120 bulls with hundreds of artificial insemination records

Conflicting results regarding alterations to sperm DNA methylation in cases of spermatogenesis defects, male infertility and poor developmental...
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Publication Biostatistics, Rau & al.

Entering into the multiverse: using multiple factor analysis to characterize individualized multi-omic regulation pathways

In an article published in the journal Biostatistics, biostatisticians from the GABI unit, in partnership with oncologists and human genomicists from...
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Comparaison des compositions des microbiotes caecaux des animaux vaccinés (en jaune) et non vaccinés (en bleu) en fonction des distances de Bray-Curtis (a.) avec l’ensemble des animaux (b.) pour chaque lignée génétique.

The composition of the caecal microbiota of laying hens infected with IBV varies according to genetic lineage and vaccination status

Vaccination of livestock is one of the most effective ways to prevent infectious diseases. The links between vaccine response and variations in the...
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A research agenda for scaling up agroecology in European countries

A profound transformation of agricultural production methods has become unavoidable due to the increase in the world’s population, and...
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@INRAE M. Dupont-Nivet

A powerful new tool for identifying genes of interest in farmed fish: a high-density chip with 665,000 genetic markers for rainbow trout

The knowledge of the variations of the DNA sequence which constitutes the genome of an individual is a central information in genetic research. If it...
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Frontiers Research Topics

The therapeutic potential of RNA transcripts: Role of mitochondria-associated non-coding RNAs in intracellular communication

This research theme aims to gather knowledge on the role of non-coding RNAs (ncRNAs) that participate in the communication pathways between...
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Integration of complex annotations in Bayesian genomic prediction models

Integration of complex annotations in Bayesian genomic prediction models

Multiple, complex, overlapping annotations.... You are wondering how is the best way to use them in your genomic prediction model? The BayesRCO open...
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