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24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal AgroParisTech Université Paris-Saclay SAPS - Sciences Animales Paris-Saclay


GABI : Génétique Animale et Biologie IntégrativeUnité Mixte de Recherche INRA - AgroParisTech

Elisabetta GIUFFRA, Senior Scientist (DR2)

Elisabetta Giuffra
Genomics of host (pig)-virus interactions and functional annotation of the genomes of major farm species.
Fond Blanc2

INRAE, UMR 1313 Génétique Animale et Biologie Intégrative
Domaine de Vilvert, Bat 320, 78352 Jouy en Josas
Tel : +33 (0) 1 34 65 26 48

Email :

Research Team: Genetics Microbiota Health (GeMS)

CV :


Elisabetta Giuffra (female), biologist, obtained her PhD in molecular genetics from the University of Turin (Italy) in 1993. Since then she worked on different topics of farm animal genomics across Italy, France, Sweden and the U.K.

Since December 2010 she works in France at INRAE (GABI Unit, Jouy-en-Josas) where she has continued her research on the genomics of host (pig) response to viruses, manly by trascriptional genomics approaches. Since her appointment as permanent senior scientist (DR2) in February 2015 she primarily works in the context of the "Functional Annotation of Animal Genomes" (FAANG) initiative (, for which she co-coordinates the Steering Committee. Since July 2019 she coordinates the H2020 FAANG project GENE-SwitCH (The regulatory GENomE of SWine and CHicken: functional annotation during development ; Recent activities are centered on the use of in vitro systems (organoids) to unravel genotype-to-phenotype relations and for in vitro phenotyping of immune-related traits in porcine populations.

Fields of Research :

Host-pathogen interaction – Functional annotation of domesticated animal genomes.

Publications and other productions :

Intestinal organoids in farm animals. Veterinary research

2021-02-25 | journal-article

Distinctive Cellular and Metabolic Reprogramming in Porcine Lung Mononuclear Phagocytes Infected With Type 1 PRRSV Strains. Frontiers in immunology

2020-12-07 | journal-article

An integrative atlas of chicken long non-coding genes and their annotations across 25 tissues. Scientific reports

2020-11-24 | journal-article

From FAANG to fork: application of highly annotated genomes to improve farmed animal production. Genome biology

2020-11-24 | journal-article

Multi-species annotation of transcriptome and chromatin structure in domesticated animals.

BMC Biology

     2019-12-30 | journal-article

Macrophage-B Cell Interactions in the Inverted Porcine Lymph Node and Their Response to Porcine Reproductive and Respiratory Syndrome Virus. Frontiers in immunology

    2019-05 | journal-article

  • PMID: 31130951
  • PMC: PMC6510060
  • DOI: 10.3389/fimmu.2019.00953

The miRNA-targeted transcriptome of porcine alveolar macrophages upon infection with Porcine Reproductive and Respiratory Syndrome Virus. Scientific reports

    2019-02 | journal-article

  • PMID: 30816147
  • PMC: PMC6395673
  • DOI: 10.1038/s41598-019-39220-3

Functional Annotation of Animal Genomes (FAANG): Current Achievements and Roadmap. Annual review of animal biosciences

    2018-11 | journal-article

  • PMID: 30427726
  • DOI: 10.1146/annurev-animal-020518-114913

Porcine Reproductive and Respiratory Syndrome Virus Type 1.3 Lena Triggers Conventional Dendritic Cells 1 Activation and T Helper 1 Immune Response Without Infecting Dendritic Cells. Frontiers in immunology

    2018-10 | journal-article

  • PMID: 30333837
  • PMC: PMC6176214
  • DOI: 10.3389/fimmu.2018.02299

Long noncoding RNA repertoire in chicken liver and adipose tissue. Genetics, selection, evolution : GSE

    2017-01 | journal-article

  • PMID: 28073357
  • PMC: PMC5225574
  • DOI: 10.1186/s12711-016-0275-0

GO-FAANG meeting: a Gathering On Functional Annotation of Animal Genomes. Animal genetics

    2016-07 | journal-article

  •  PMID: 27453069
  •  PMC: PMC5082551
  •  DOI: 10.1111/age.12466

Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project. Genome Biology

    2015-03 | journal-article

  •  PMID: 25854118
  •  PMC: PMC4373242
  •  DOI: 10.1186/s13059-015-0622-4

Impact of the genetic background on the composition of the chicken plasma MiRNome in response to a stress. PloS one

    2014-12 | journal-article

  • PMID: 25473826
  • PMC: PMC4256448
  • DOI: 10.1371/journal.pone.0114598

A 2.5-kilobase deletion containing a cluster of nine microRNAs in the latency-associated-transcript locus of the pseudorabies virus affects the host response of porcine trigeminal ganglia during established latency. Journal of virology

    2014-10 | journal-article

  •  PMID: 25320324
  •  PMC: PMC4301172
  •  DOI: 10.1128/JVI.02181-14