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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal AgroParisTech Université Paris-Saclay


GABI : Génétique Animale et Biologie IntégrativeUnité Mixte de Recherche INRA - AgroParisTech

Marie-Pierre SANCHEZ, Engineer

Marie-Pierre SANCHEZ
Genetic determinism of traits in cattle

INRAE, UMR 1313 Génétique Animale et Biologie Intégrative
Domaine de Vilvert, Bat 211, 78352 Jouy en Josas
Tel : +33 (0) 1 34 65 21 82

Email : marie-pierre.sanchez(at)

Research Team: Bovine Genetics and Genomics

CV :

  • Engineer INRAE
    • Since 2012: Cattle Genetics (G2B team)
    • 2000-2012: Pig Genetics
    • 1998-2000: Fish Genetics
  • 2016-2019: PhD thesis from Université Paris-Saclay, prepared at AgroParisTech, majoring in Animal Genetics
  • 1998: Master of Population Biology, Genetics and Ecoethology, minor in Quantitative Genetics, AgroParisTech, University of Tours, University of Rennes

Fields of Research :

Analysis of genetic variability of traits; Detection, fine mapping and characterization of QTL; Genetic determinism of milk composition and cheese-making traits; Genetic determinism of resistance to paratuberculosis; Quantitative Genetics; Genomic Selection

Other Activites :

  • Quality correspondent of the ISO9001 certified perimeter "Genetic evaluation of bovine breeding animals" (2013-2018)
  • Teaching (Master Priam)

Publications :

Sanchez M.P., Fritz S., Patry C., Delacroix-Buchet A., Boichard D. 2020. Milk protein variant and haplotype frequencies estimated from genotypes of more than one million bulls and cows of twelve French cattle breeds. J Dairy Sci, 103, ehead of print.

Van Den Berg I., Xiang R., Jenko J., Pausch H., Boussaha M., Tribout T., Gjuvsland A.B., Boichard D., Nordbø Ø., Sanchez M-P., Goddard M.E. 2019. Large scale multi breed meta-analysis for fat and protein percentage using imputed sequence variant genotypes in 94,321 cattle from eight dairy breeds. Genet Sel Evol, 52, 37.

Sanchez M.-P., Guatteo R., Davergne A., Grohs C., Taussat S., Fritz S., Boussaha M., Blanquefort P., Delafosse A., Joly A., Schibler L., Fourichon C., Boichard D. 2020. Identification of the ABCC4, IER3, and CBFA2T2 candidate genes for resistance to paratuberculosis from sequence-based GWAS in Holstein and Normande dairy cattle. Genet Sel Evol 52:14.

Laithier C., Wolf V., Brochard M., Sanchez M.-P., Gaudillière N., Minéry S., Fritz S., Gavoye S., Gaüzère Y., Rolet-Répécaud O., Notz E., Bouton Y., Boichard D., Grosperrin P. and Delacroix-Buchet A. 2020. FROM’MIR : Développer des outils de prédiction et de conseil pour maîtriser la fromageabilité des laits destinés à la fabrication des fromages traditionnels franc-comtois. Innovations Agronomiques 79, 227-244.

Sanchez M.P., Wolf V., Laithier C., El Jabri M., Beuvier E., Rolet-Repecaud O., Gaudilliere N., Minery S., Ramayo-Caldas Y., Tribout T., Michenet A., Boussaha M., Taussat S., Fritz S., Delacroix-Buchet A., Grosperrin P., Brochard M., Boichard D. 2019. Analyse génétique de la fromageabilité du lait de vache prédite par spectrométrie moyen infrarouge en race Montbéliarde. INRAE Prod Anim, 32, 379-398.

Sanchez M.P., Ramayo-Caldas Y., Wolf V., Laithier C., El Jabri M., Michenet A., Boussaha M., Taussat S., Fritz S., Delacroix-Buchet A., Brochard M., Boichard D. 2019. Sequence-based GWAS, network and pathway analyses reveal genes co-associated with milk cheese making properties and milk composition in Montbéliarde cows. Genet Sel Evol, 51, 34.

El Jabri M., Sanchez M.P., Trossat P., Laithier C., Wolf V., Grosperrin P., Beuvier E., Rolet-Répécaud O., Gavoye S., Gauzere Y., Belysheva O., Notz E., Boichard D., Delacroix-Buchet A. 2019. Comparison of Bayesian and PLS regression methods for mid-infrared prediction of cheese-making properties in Montbéliarde cows. J Dairy Sci., 102:6943–6958.

Sanchez M.P., El Jabri M., Minery S., Wolf V., Beuvier E., Laithier C., Delacroix-Buchet A., Brochard M., Boichard D. 2018. Genetic parameters for cheese-making properties and milk composition predicted from mid-infrared spectra in a large dataset of Montbéliarde cows. J Dairy Sci, 101, 10048–10061.

Sanchez M.P., Wolf V., El Jabri M., Beuvier E., Rolet-Repecaud O., Gauzere Y., Minery S., Brochard M., Michenet A., Taussat S., Barbat-Leterrier A., Delacroix-Buchet A., Laithier C., Fritz S., Boichard D. 2018. Short-communication: Confirmation of candidate causative variants on milk composition and cheese-making properties in Montbéliarde cows. J Dairy Sci, 101, 10076–10081.

Bouwman A.C., Daetwyler H.D., Chamberlain A.J., Hurtado Ponce C., Sargolzaei M., Schenkel F.S., Sahana G., Govignon-Gion A., Boitard S., Dolezal M., Pausch H., Brøndum R.F., Bowman P.J., Thomsen B., Guldbrandtsen B., Lund M.S., Servin B., Garrick D.J., Reecy J., Vilkki J., Bagnato A., Wang M., Hoff J.L., Schnabel R.D., Taylor J.F., Vinkhuyzen A.A.E., Panitz F., Bendixen C., Holm L.E., Gredler B., Hozé C., Boussaha M., Sanchez M.P., Rocha D., Capitan A., Tribout T., Barbat A., Croiseau P., Drögemüller C., Jagannathan V., Vander Jagt C., Crowley J.J., Intergenomics Consortium, Bieber A., Purfield D.C., Berry D.P., Emmerling R., Götz K.U., Van Tassell C.P, Fries R., Stothard P., Veerkamp R.F., Boichard D., Goddard M.E., Hayes B.J.  2018. Meta-analysis of genome wide association studies for the stature of cattle reveals common genes that regulate size in mammals. Nature Genetics, 50, 362-367.

Teissier M., Sanchez M-P., Boussaha M., Barbat-Leterrier A., Hozé C., Robert-Granié C., Croiseau P. 2018. Use of meta-analyses and joint analyses to select variants in whole genome sequences for genomic evaluation : an application in milk production of French dairy cattle breeds. J Dairy Sci. 101: 3126-3139.

Sanchez M.P., Govignon-Gion A., Croiseau P., Fritz S., Hoze C., Miranda G., Martin P., Barbat-Leterrier A., Brochard M., Boussaha M., Boichard D. 2017. Within-breed and multi-breed GWAS on imputed whole genome sequence variants reveal candidate mutations affecting milk protein composition in dairy cattle. Genet Sel Evol, 49:68.

Jonas D., Ducrocq V., Fritz S., Baur A., Sanchez M.P., Croiseau P. 2017. Genomic evaluation of regional dairy cattle breeds in single-breed and multibreed contexts. Journal of Animal Breeding and Genetics, 134:3-13.

Sanchez M.P., Govignon-Gion A., Ferrand M., Gele M., Pourchet D., Miranda G., Martin P., Brochard M., Boichard D. 2017. Short-communication: Genetic parameters for milk protein composition in the French Montbéliarde, Normande and Holstein dairy cattle breeds. J Dairy Sci, 100, 6371-6375.

Sanchez M.P. , Govignon-Gion A., Ferrand M., Gele M., Pourchet D., Amigues Y., Fritz S., Boussaha M., Capitan A., Rocha D., Miranda G., Martin P., Brochard M., Boichard D. 2016. Whole genome scan to detect SNP associated to milk protein composition in three French dairy cattle breeds. J Dairy Sci, 99, 8203–8215.

Boichard D., Govignon-Gion A., Larroque H., Maroteau C., Palhiere I., Tosser-Klopp G., Rupp R., Sanchez M.P., Brochard M. 2014. Déterminisme génétique de la composition en acides gras et protéines du lait des ruminants. INRA Prod Anim, 27, 283-298.

Legarra A., Croiseau P., Sanchez M.P., Teyssèdre S., Sallé G., Allais S., Fritz S., Moreno C., Ricard A., Elsen J.M. 2014. A comparison of methods for whole-genome QTL fine mapping using dense markers in four livestock species. Genet. Sel. Evol., 47:6.

San Cristobal M., Sanchez M.P., Mercat M.J., Rohart F., Liaubet L., Tribout T., Canlet C., Muller N., Molina J., Iannucelli N., Laurent B., Villa-Vialaneix N., Paris A., Milan D. 2014. Le métabolome, un moyen pour trouver de nouveaux biomarqueurs ? Viandes et produits carnés 2014-30-2-1.

Sanchez M.P., Tribout T., Iannuccelli N., Bouffaud M., Servin B., Dehais P., Muller D., Tenghe A., Mercat M.J., Bidanel J.P., Rogel-Gaillard C., Milan D., Gilbert H. 2014. Genome wide association study in a Large White commercial population for production traits: evidence of a haplotype affecting meat quality traits. Genet. Sel. Evol., 46:12.

Hernandez S.C., Hogg C.O., Billon Y., Sanchez M.P., Bidanel J.P., Haley C.S., Archibald A.L., Ashworth C.J. 2013. Secreted phosphoprotein 1 expression in endometrium and placental tissues of Hyperprolific Large white and Meishan gilts. Biology of Reproduction. 88, 120.

Gondret F., Riquet J., Tacher S., Demars J., Sanchez M.P., Billon Y., Robic A., Bidanel J.P., Milan D. 2011. Towards candidate genes affecting body fatness at SSC7 QTL by expression analyses. Journal of Animal Breeding and Genetics. 129, 316-324.

Tortereau F., Sanchez M.P., Feve K., Gilbert H., Iannuccelli N., Billon Y., Milan D., Bidanel J.P., Riquet J. 2011. Progeny-testing of full-sibs IBD on a SSC2 QTL region highlights epistatic interactions for fatness traits in pigs. BMC Genetics. 12, 92.

Riquet J., Gilbert H., Servin B., Sanchez M.P., Iannuccelli N., Billon Y., Milan D., Bidanel J.P. 2011. A locally congenic backcross design in pig : a new regional fine QTL mapping approach miming congenic strains used in mouse. BMC Genetics. 12, 6.

Sanchez M.P., Iannuccelli N., Basso B., Foury A., Billon Y., Gandemer G., Gilbert H., Mormède P., Bidanel J.P., Larzul C., Riquet J., Milan D., Le Roy P. 2011. Microsatellite mapping of QTL affecting meat quality, stress hormones and production traits in Duroc x Large White F2 pigs. Animal 5, 167-174.

Demars J., Riquet J., Sanchez M.P., Billon Y., Hocquette J.F., Lebret B., Iannuccelli N., Bidanel J.P., Milan D., Gondret F. 2007. Metabolic and histochemical characteristics of fat and muscle tissues in homozygous or heterozygous pigs for the body composition QTL located on chromosome 7. Physiol Genomics 30: 232-241.

Sanchez M.P., Iannuccelli N., Basso B., Bidanel J.P., Billon Y., Gandemer G., Gilbert H., Larzul C., Legault C., Riquet J., Milan D., Le Roy P. 2007. Identification of QTL with effects on intramuscular fat content and fatty acid composition in a Duroc x Large White cross. BMC Genetics, 8:55.

Damon M., Louveau I., Lefaucheur L., Lebret B., Vincent A., Le Roy P., Sanchez M. P., Herpin P., Gondret F. 2006. Number of intramuscular adipocytes and fatty acid binding protein-4 content are significant indicators of intramuscular fat level in crossbred Large White X Duroc pigs. Journal of Animal Science, 84, 1083-1092.

Sanchez M.P., Riquet J., Iannuccelli N., Gogué J., Demeure O., Billon Y., Caritez J.C., Burgaud G., Fève K., Bonnet M., Péry C., Lagant H., Le Roy P., Bidanel J.P., Milan D. 2006. Effects of QTL on chromosomes 1, 2, 4 and 7 for growth, carcass and meat quality traits in backcross Meishan x Large White pigs. Journal of Animal Science, 84, 526-537.

Demeure O., Sanchez M.P., Riquet J., Iannuccelli N., Demars J., Feve K., Gogue J., Billon Y., Caritez J.C., Milan D., Bidanel J.P. 2005. Exclusion of the SLA as candidate region and reduction of the position interval for the porcine chromosome 7 QTL affecting growth and fatness. Journal of Animal Science, 83, 1979-1987.

Foury A., Devillers N., Sanchez M.P., Griffon H., Le Roy P., Mormède P. 2005. Stress hormones, carcass composition and meat quality in Large White x Duroc pigs. Meat Science, 69, 703-707.

Mambrini M., Sanchez M.P., Chevassus B., Labbé L., Quillet E., Boujard T 2004. Selection for growth increases feed intake and affects feeding behavior of brown trout. Livestock Prod. Sci., 88, 85-98.

Mambrini M., Médale F., Sanchez M.P., Recalde B., Chevassus B., Labbé L., Quillet E., Boujard T 2004. Selection for growth in brown trout increases feed intake capacity without affecting maintenance and growth requirements. J. Anim. Sci., 82, 2865-2875.

Sanchez M.P., Bidanel J.P., Zhang S., Naveau J., Burlot T., Le Roy P. 2003. Likelihood and bayesian approaches reveal major genes affecting body composition, carcass, meat quality and number of good teats in a Chinese European pig line. Genet. Sel. Evol., 35, 385-402.

Sanchez M.P., Chevassus B., Labbé L., Quillet E., Mambrini M. 2001. Selection for growth of brown trout (Salmo trutta) affects feed intake but not feed efficiency. Aquat. Living Resour., 14, 41-48.