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Last update: May 2021

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Axes of research

The research conducted at PROSE on environmental biotechnologies is built along 3 major axes:

1. Elementary process analysis with cutting-edge analytical approaches and in line data acquisition, from lab scale to industrial scale

  • Metaomics, instrumentation, knowledge representation models
Ecological consequences of abrupt temperature changes in anaerobic digesters.Electrical resistivity tomography used to characterize bubble distribution in complex aerated reactors: Development of the method and application to a semi-industrial MBR in operation

2. Knowledge integration and coupling for engineering, by database development, data treatment tools (bioinformatics and biostatistics) and coupled bio-physico-chemical modeling

  • Data driven approaches: database, data analysis, development of indicators
Integrative analyses to investigate the link between microbial activity and metabolites degradation during anaerobic digestionA Generic Multivariate Framework for the Integration of Microbiome Longitudinal Studies With Other Data Types
  • Biology/physics/chemistry coupled modeling and study of emerging properties from these couplings
Considering the plug-flow behavior of the gas phase in nitrifying BAF models significantly improves the prediction of N2O emissionsConsistent microbial dynamics and functional community patterns derived from first principles

3. Bioprocesses optimization and innovation, by lifting scientific and technical barriers against implementation of innovative processes and by real scale testing

  • Bioelectrochemical processes for environmental biorefinery, optimization of existing processes, model-assisted design
Schéma de principe d'un pilote bioélectrochimique pour la biorafinnerie environnementalePilote bioélectrochimique TRL4 pour la biorafinnerie environnementale